Cinnamon is known for its warm and sweet flavour, but it has a lot more to offer than its culinary applications. Cinnamon has been valued for centuries for its medicinal properties, and research shows it can be effective in reducing high blood pressure, regulating glucose levels, reducing inflammation, and improving cognition.

Cinnamon is rich in polyphenols, which are plant compounds known for their antioxidant properties. These polyphenols, including procyanidins and cinnamaldehyde, exhibit strong antioxidant activity, protecting cells from oxidative stress and damage caused by free radicals. Cinnamaldehyde has been shown to inhibit the release of pro-inflammatory cytokines in the gut, thus aiding in the reduction of gut inflammation and promoting gut health.

Cinnamon also exhibits prebiotic-like activity, supporting the growth of beneficial gut bacteria and suppressing the growth of pathogenic bacteria, positively impacting the balance of the gut microbiome. Several studies in healthy adults have demonstrated that cinnamon extract significantly increased the abundance of Bifidobacteria, Akkermansia and Lactobacillus, all known for their beneficial effects on gut health.

Studies have also shown that cinnamon oil can improve the oral microbiome by exhibiting a broad range of antimicrobial activity against the microbes causing dental caries. This is significant as dental caries is a risk factor for heart disease and Metabolic Syndrome.

Cinnamon also has many nutritional benefits. Adding one teaspoon (2-4 grams) of cinnamon powder a day provides calcium, potassium, vitamin A as well as small quantities of fibre and trace amounts of many other vitamins and nutrients.

So be bold and start adding cinnamon to your food and reap the benefits of its exotic taste whilst also supporting your gut microbiome and promoting optimal health.

REFERENCES

Jeong. et al. (2021). Antibacterial and antibiofilm activities of cinnamon essential oil nanoemulsion against multi-species oral biofilms. Sci Rep 11, 5911. DOI: 10.1038/s41598-021-85375-3

Kim et al. (2019). “Severity of dental caries and risk of coronary heart disease in middle-aged men and women: a population-based cohort study of Korean adults, 2002–2013.” Scientific Reports 9:10491 DOI: 10.1038/s41598-019-47029-3

Lu et al. (2019). “Mixed Spices at Culinary Doses Have Prebiotic Effects in Healthy Adults: A Pilot Study” Nutrients 11, no. 6: 1425. DOI: 10.3390/nu11061425

Lu et al. (2017). “Prebiotic Potential and Chemical Composition of Seven Culinary Spice Extract” Journal of Food Science Aug; 82(8): 1807–1813 DOI: 10.1111/1750-3841.13792

Mollazadeh et al. (2016). “Cinnamon effects on metabolic syndrome: a review based on its mechanisms.” Iran J Basic Med Sci. Dec; 19(12):1258-1270. DOI: 10.22038/ijbms.2016.7906.

Rao PV, Gan SH. (2014). “Cinnamon: a multifaceted medicinal plant.” Evid Based Complement Alternat Med. 642942. DOI: 10.1155/2014/642942

Vicky Ellenport BHSc NUT is a registered Nutritionist and Microbiome Analyst who uses a food first approach in her treatment protocols.

What is the Thyroid?

The thyroid is a butterfly-shaped gland that is located in the front of your neck, just below the larynx (Adam’s apple). It is not visible when it is functioning properly.

The thyroid gland produces hormones that regulate many of your body’s functions including metabolism, growth, heart, muscle and digestive function, nervous system, temperature regulation, cognitive function and bone maintenance.

How does the Thyroid work?

The thyroid gland uses the amino acid tyrosine and iodine from the foods you eat to synthesise two main hormones which are carried to all the cells in the body.

These hormones are known as the Thyroid Hormones.

• Triiodothyronine (T3)
• Thyroxine (T4)

The thyroid gland produces around 20% of T3, the highly active form of the hormone, and 80% of T4, a prohormone which is converted to the active T3 form by specific enzymes in tissues such as the liver and kidneys.

The levels of T3 and T4 are maintained in the body through the release of the Thyroid Stimulating Hormone (TSH). The Pituitary gland, which is located at the base of your brain, responds to low levels of thyroid hormone in the blood by releasing TSH which tells your thyroid gland to increase thyroid hormone production.

In addition to TSH levels in the blood, the pituitary gland is regulated by the hypothalamus in the brain which releases TSH Releasing Hormone which tells the pituitary gland when to release TSH to stimulate the thyroid gland.

This complex system is known as the Hypothalamus-Pituitary-Thyroid Axis (HPT Axis) which functions to maintain normal levels of thyroid hormones circulating in the body.

What could go wrong?

When everything is functioning “normally”, the thyroid gland produces the right levels of thyroid hormones to support healthy metabolism and body function.

However, when the HPT Axis is disrupted, the thyroid may produce too much or too little thyroid hormones.

Thyroid function may be disrupted by a nutrient-poor diet, stress, trauma, environmental toxin exposure, viral or bacterial infection, gut dysbiosis, nutrient deficiencies, inflammation or autoantibodies.

Autoantibodies are associated with autoimmune thyroid disease (AITD), which is the most common cause of thyroid dysfunction.

What is Autoimmune thyroid disease?

AITD can be either Hasimoto’s or Graves’ Disease and both result in thyroid dysfunction.

Hashimoto’s Disease occurs when the body’s immune system attacks the thyroid gland causing increased inflammation and destruction of thyroid cells, resulting in a decrease of thyroid hormones (hypothyroidism).

When your thyroid is underactive it does not make enough thyroid hormone to support normal metabolism and body functions. Hypothyroid symptoms may include weight gain, constipation, joint or muscle pain, fatigue, feeling cold, thinning dry hair, sadness or depression, heavy menstrual bleeding etc.
Hypothyroidism affects more women than men.

Graves’ Disease occurs when the immune system stimulates the thyroid to produce too much hormone – hyperthyroidism.

When your body has too much thyroid hormone, the body’s processes speed up and cause symptoms including weight loss, rapid heartbeat, increased bowel movements or diarrhoea, increased sweating, anxiety or nervousness, sleep issues, trembling hands, fewer and lighter menstrual bleeds etc.

Autoimmune Thyroid Disease and other Autoimmune Conditions

Hashimoto’s Thyroiditis is the most prevalent autoimmune disease and is frequently associated with other autoimmune conditions.

AITD may occur concurrently with coeliac disease, rheumatoid arthritis, systemic lupus erythematous and Sjogren’s syndrome.

How is Thyroid dysfunction diagnosed?

Thyroid conditions can be difficult to diagnose as many of the symptoms are common to other medical conditions. However,  a detailed client and family history can often provide an indication that the thyroid needs to be tested.

Blood Tests:

TSH: High TSH indicates low thyroid function while low TSH indicates an overactive thyroid.

T3: the active form of the thyroid hormone

T4: the prohormone that becomes the active form through conversion in the liver and kidneys

Reverse T3 (rT3): an inactive form of T3 that cannot be used by the body. A high rT3 indicates an issue with T4 to T3 conversion.

Anti-thyroglobulin AB (TRAb) and Anti-TPO AB are thyroid antibodies that are elevated in autoimmune conditions such as Hashimoto or Graves’ disease.

Testing the full thyroid panel is very important in diagnosing thyroid conditions properly.

Ultrasound

A thyroid ultrasound identifies whether there have been any structural changes such as the presence of nodules or cysts or enlargement of the thyroid gland.

Fine Needle Biopsy

A sample of cells may be collected from a nodule during the ultrasound to identify cells that may be cancerous.

Can AIP help manage Autoimmune Thyroid Disease?

The conventional treatment for AITD is through the prescription of medication to replace thyroid hormone in the case of Hashimoto’s Disease, or medication to suppress thyroid hormone for Graves’ Disease. Complementary treatment works side by side the medical treatment.

The Autoimmune Protocol (AIP) is used to identify dietary triggers, reduce inflammation, and improve thyroid symptoms. Several studies have shown that people with Hashimoto’s, continue to have debilitating symptoms even while taking thyroid medication. The AIP helps eliminate the symptoms the medication doesn’t address. Efficacy of the Autoimmune Protocol Diet as Part of a Multi-disciplinary, Supported Lifestyle Intervention for Hashimoto’s Thyroiditis (nih.gov).

In addition, nutritional supplements may be prescribed such as zinc, selenium, vitamin D, and iodine to support healthy thyroid function. Managing stress, improving sleep, and increasing physical activity are also important components of the AIP.

Read more about the AIP here: Healing Autoimmune Disease Naturally | The Nutrition Factor – Vicky Ellenport | Clinical Nutritionist Melbourne).

If you have been diagnosed with a thyroid disorder or an autoimmune condition and want to know more about managing AID naturally, please book in for a complimentary Discovery Session with Vicky Book Appointment (thenutritionfactor.com.au) to find out how AIP may be helpful for you.

Factors that lead to the development of IBD are complex but immune dysregulation, gut dysbiosis, a nutritionally poor diet, environmental factors (such as mould, lead and other toxin exposure), stress, inadequate sleep, and family history are contributing factors.

The symptoms of both UC and CD can be similar and may include abdominal cramps and pain, diarrhoea, constipation, urgency for bowel movements, incomplete bowel evacuation, rectal bleeding, mucus in stools, fever, reduced appetite, weight loss and fatigue.

In both conditions, symptoms follow a pattern of flare and remission, with severity ranging from mild to severe.

Despite sharing these characteristics, Ulcerative Colitis and Crohn’s Disease are different conditions.

Ulcerative Colitis causes swelling and ulcers on the mucosal surface of the lining of the colon and rectum. These ulcers may cause bleeding and discharge mucus or pus. This loss of blood in the stools can lead to Iron Deficiency Anaemia.  UC causes a continuous area of damage along, the large intestine beginning at the anus and spreading upward along the colon, rather than appearing as patches of damage.

Crohn’s Disease causes inflammation in the deeper layers of the mucosal tissue of the intestine and can extend through the entire thickness of the bowel wall. CD can affect several patches along the length of the colon and extend into the small intestine. Inflammation in the small intestine disrupts the proper absorption of nutrients from food and can cause elimination of fats and nutrients due to diarrhoea.

How is IBD diagnosed?

Diagnosis begins with a detailed case history exploration to understand when and how symptoms began, assess the severity of the symptoms and identify factors that exacerbate and alleviate the symptoms.

Tests used to diagnose IBD include:

Blood Tests may be used to detect inflammation, autoimmune antibodies, nutrient deficiencies (eg iron, vitamin B12, vitamin D etc).

Stool Tests for the presence of blood, pathogens or inflammation markers.

Gastroscopy

• Colonoscopy to identify inflammation, bleeding or ulcers in the large intestine.
• Sigmoidoscopy is similar to a colonoscopy but only examines the rectum and lower part of the colon.
• Upper Endoscopy is used to examine the small intestine for inflammation, bleeding or ulceration.

Biopsy: tissue may be removed during a gastroscopy to help differentiate between CD and UC.

Imaging Tests such as X-ray, CT scan or MRI may show inflammation, bleeding or ulcers and are often used to differentiate between UC and CD.

Is IBD different from IBS?

Yes!

Though the symptoms may appear to be the same, IBS and IBD are distinctly different conditions.

Inflammatory Bowel Disease is an immune-mediated disease that causes inflammation and damage to the gastrointestinal tract which can be seen during diagnostic imaging.

Irritable Bowel Syndrome is a syndrome, or group of symptoms, that are not caused by the immune system. They may develop due to food intolerances, microbial infection, family history or mood disorder (anxiety/depression).  There is no apparent inflammation in IBS and it does not cause any visible damage or abnormality to the gastrointestinal tract.

Managing Inflammatory Bowel Disease with AIP

While autoimmune diseases cannot be cured, careful diet, nutritional supplementation and lifestyle planning can help to improve your symptoms, reduce the severity of IBD flares and maintain longer periods of remission.

The Autoimmune Protocol (AIP) is a complementary approach to chronic disease management which focuses on healing the gut to improve immune regulation and reduce the chronic inflammation that causes tissue damage. Trigger foods are eliminated until symptoms resolve and then slowly reintroduced to determine what foods are causing your symptoms. Healing is supported by improving lifestyle factors such as stress reduction, exercise and improved sleep quality.

Recent studies have shown that the AIP diet is an effective adjunct to medical treatment of Inflammatory Bowel Disease. (Clinical Course and Dietary Patterns Among Patients Incorporating the Autoimmune Protocol for Management of Inflammatory Bowel Disease (P12-010-19) | Current Developments in Nutrition | Oxford Academic (oup.com))

You can read more about the AIP here: Healing Autoimmune Disease Naturally | The Nutrition Factor – Vicky Ellenport | Clinical Nutritionist Melbourne

If you have been diagnosed with IBD and would like to know more about the Autoimmune Protocol or how I can help you manage your autoimmune symptoms, book in for a complimentary Discovery Session here: Book Appointment (thenutritionfactor.com.au)

The process of getting an AID diagnosed can be so long, drawn out and frustrating that it is not uncommon for people with AID to be labelled a hypochondriac – a person who fears they are living with a serious, undiagnosed medical condition despite diagnostic tests showing that there is nothing wrong with them – especially in the early stages of illness.

On average, a person will see 5 doctors over the course of several years to finally receive an autoimmune disease diagnosis.

Autoimmune Disease Symptoms

While different autoimmune diseases affect different organs and systems in the body, what they all have in common is that they occur when the body’s immune system mistakenly attacks its own cells.

Autoantibodies are immune proteins that target the body’s own healthy tissue when the immune system fails to distinguish between “self” and “non-self”.

The continual attack on the body’s cells causes inflammation and sufficient tissue damage that symptoms of disease begin to emerge.

People with an autoimmune disease may describe long-term struggles with a wide range of symptoms such as: fatigue, gastrointestinal issues, joint pain, recurring infections, skin problems, allergies, migraines, unexplained weight changes, anxiety/depression, low/high blood pressure and more.

Why does it take so long to get an autoimmune disease diagnosis?

• Common, non-specific symptoms. The symptoms of autoimmune conditions vary widely and are generally non-specific, that is, symptoms that may describe any one of a variety of conditions. In the early stages of the illness people will usually present to their doctor or health professional for help with one, primary complaint (e.g., recurring urinary tract infection or persistent acne or inability to lose weight) and many of the other symptoms they are experiencing do not get mentioned. It is not until the practitioner has a full picture of ALL the symptoms, together with a full health history, that the connection between the symptoms becomes clearer, and that the possibility of an AID may become apparent.
• Remission/flare pattern. It is possible for an AID to enter a period of remission, where a person may have very mild symptoms, or even be asymptomatic, for a period. At this time, for an undiagnosed person, it may seem that the illness has resolved and is all but forgotten about. However, when triggered, AID can enter a flare phase when symptoms return suddenly and severely leaving the sufferer exhausted, depleted and in pain.
• Asymptomatic or slow to develop signs and symptoms. Not all Autoimmune Diseases cause symptoms immediately. It is possible to live with an AID for many years before symptoms become apparent or before an incident occurs that leads to an AID diagnosis. For example, ankylosing spondylitis symptoms may develop very gradually and often goes undiagnosed for several years, before it becomes visible on an x-ray. Likewise, Type 1 diabetes involves a gradual destruction of the pancreatic beta cells and it is only diagnosed once 90% of the cells have been destroyed.
• Co-Conditions. It is possible to have more than one AID, in fact having one AID increases the chances of you developing another. When there is more than one AID present, it is possible for one to mask the other. For example you may have been diagnosed with Rheumatoid Arthritis, but in actual fact you also may have Coeliac Disease, the symptoms of which contribute to joint pain, but remains undiagnosed if there are no other obvious symptoms.
• Every person is different and, with AID affecting a wide variety of organs and causing such varied symptoms, each presentation of each condition can be different. It is possible that two people may be diagnosed with the same condition with very different symptoms. Alternatively, two people with the same symptoms may be affected by different conditions.

Risk Factors for Autoimmune Disease.

Certain risk factors are known to increase the chances of developing an autoimmune disorder. The presence of any one of these risk factors, along with a description of all the symptoms, can help to get closer to an AID diagnosis.

• Genetics. While members of the same family may suffer from different autoimmune conditions, a predisposition to autoimmune disease does appear to run in families.
• Excess weight is associated with increased risk of developing an AID that affects the joints such as Rheumatoid and Psoriatic Arthritis. In addition, adipose tissue, or fat, secretes pro-inflammatory compounds that cause low-grade chronic inflammation and dysregulation of the immune system.
• Smoking. The toxic chemicals that are released when tobacco is burned impacts the immune system by causing inflammation, suppressing immune function, and stimulating the production of autoantibodies.
• Certain medications. The side effects of some pharmaceuticals that are widely used daily can have side effects that involve the immune system and can lead to an autoimmune reaction.
• Infection with a virus, such as Epstein Barr Virus (EBV), or bacteria, such as Streptococcus, can turn on genes that impede the immune system’s ability to differentiate between self and non-self, initiating an autoimmune reaction.

Are there tests for Autoimmune Disease?

There is no single test to diagnose AID but rather a selection of markers in blood or urine samples which, when put together with the presenting symptoms can lead to an AID diagnosis.

• Autoantibodies: The presence of autoantibodies may indicate an autoimmune disease.
  • Antinuclear Antibody (ANA) Test. A high level of these autoantibodies may be used to diagnose a systemic AID such as lupus and may be used to rule out other conditions with similar symptoms
  • Rheumatoid Factor (RF) is used to diagnose Rheumatoid Arthritis (RA). A positive test for RF differentiates RA from osteoarthritis and other connective tissue disorders.
  • Thyroid Antibody test (TPO) is used to diagnose Hashimoto’s or Graves disease in conjunction with other thyroid testing.
• Inflammation Markers: C-Reactive Protein (CRP) and Erythrocyte Sedimentation Rate (ESR) are used to detect the presence of inflammation, a common characteristic symptom of all AID’s.
• X-Rays, Gastroscopes and Biopsies: may be used to confirm or support an AID diagnosis.

Why do you need a diagnosis?

• Many people suffer with symptoms for many years and finally having a diagnosis can be a validation that it was not just in their mind.
• Knowing what is causing your symptoms allows your health practitioner to tailor a treatment plan specific to your needs.
• Having a diagnosis means that your health care team can anticipate, and help to reduce the risk, of disease progression or future complications.
• It helps you educate yourself and gain a better understanding about your condition and how to manage it.
• It reminds you that you are not alone, and that you can reach out and connect with others with the same condition so that you may support one another.

You have been diagnosed with an autoimmune disease, so what now?

Once you receive an AID diagnosis, the treatment approach is up to you. As there is no proven cure for AID, treatment is aimed at improving symptoms and promoting remission.

One option is the conventional medicine approach which prescribes pharmaceutical medications to manage symptoms and induce remission.

The other option is the natural medicine approach which aims to determine the underlying cause of your AID and to tailor a treatment plan to improve your symptoms and reduce the frequency of flare-ups.

As a natural medicine practitioner Vicky works in conjunction with your medical team, using a holistic approach to managing AID that encompasses thorough testing, identification of nutritional deficiencies, lifestyle and dietary recommendations and stress management techniques.

If you have been struggling with a long-term, undiagnosed health issue, or if you have recently been diagnosed with an AID, book in for a complimentary Discovery Session with Vicky to discuss the best options for managing your health.

First of all, it is important to know that not all inflammation is bad.

Inflammation is the immune system’s response to injury or infection. It is a protective mechanism which helps to contain and limit the amount of damage caused when the body is affected by pathogens, environmental chemicals, physical injury (cuts, scrapes, bites, stings etc) or radiation. This is acute inflammation and it helps the body heal and fight infection. Acute inflammation presents as pain, redness, swelling, heat or loss of function and usually resolves in a few days to a couple of weeks.

Chronic inflammation is long-term inflammation that may not resolve for a period of months to years. Instead of healing, chronic inflammation can actually be the cause of the disease.

What causes chronic inflammation?

• Persistence of an acute inflammation such as injury or infection.
• Diet high in processed foods and sugar
• Unresolved leaky gut.
• Prolonged exposure to environmental irritants such as chemicals or pollution.
• A defect in the cells that mediate and regulate the immune response.
• Autoimmune disorders, in which damage is caused when the immune system mistakenly attacks the body’s own, healthy tissue.

Chronic inflammation can lead to significant damage to cells, tissues and organs. The extent of the damage varies depending on the cause of the injury that initiated the inflammation, and the body’s ability to repair and overcome it.

Inflammation is associated with chronic diseases such as Type 2 Diabetes, Stroke, Heart disease, Cancer and Autoimmune diseases including Inflammatory Bowel Disease (IBD), Rheumatoid Arthritis, Multiple Sclerosis, Type 1 Diabetes and Systemic Lupus Erythematosus (SLE).

Inflammation can be both the cause of a health condition or else it may be a symptom, but either way, reducing inflammation is crucial to managing and overcoming chronic illness.

Inflammation in Autoimmune Disease

Autoimmune Disease (AID) is caused by immune system dysfunction and like all chronic illness, inflammation plays a central role in the severity of the symptoms.

Each AID may be characterized by different symptoms however the common link between them all is that they are driven by chronic inflammation.

So, what causes inflammation in AID?

In AID, inflammation may be triggered by poor nutrition, excessive stress, lack of quality sleep and physical activity.

• Foods including processed and fried foods, refined carbohydrates (sugar, flour etc), gluten, grains, and dairy can promote inflammation.
• Physical inactivity can lead to the accumulation of visceral fat which promotes inflammation. Conversely, over-exercising can also create inflammation.
• Stress and lack of Sleep can create an imbalance in the immune system causing it to become overactive, attacking healthy tissue and causing inflammation.

How Does the Autoimmune Protocol (AIP) help to reduce inflammation?

The AIP is designed to reduce inflammation by removing those diet and lifestyle factors that promote inflammation.

Top 5 Strategies to reduce inflammation:

1. Eat the rainbow. Include a colourful variety of fruits and vegetables, including plenty of dark green leafy vegetables. Phytonutrients are natural compounds which impart colour, flavour and aroma in plant foods. These phytonutrients provide immune-supportive antioxidants which can suppress inflammation.
2. Add culinary spices. Turmeric, ginger, garlic, cloves, cinnamon. Add these anti-inflammatory and antioxidant spices into your cooking to reduce inflammation. These spices are from flowers, roots, bark or leaves of plants and are safe to have on the AIP diet, while spices made from seeds, berries and fruits (cumin, coriander, pepper, cardamom, chilli etc), are to be avoided during the elimination phase of the AIP diet.
3. Don’t forget Vitamin D. Vitamin D plays an essential role in modulating immune function and regulating the biochemical pathways that are involved in inflammation. Low vitamin D levels may cause symptoms to worsen in people with chronic illness such as AID. Vitamin D may be absorbed through the skin directly from the sun. During the Southern Hemisphere’s Spring and Summer months 10-15 minutes of unprotected sun exposure before 10am or after 3pm provides a good, safe dose of vitamin D. Vitamin D is also found in foods such as salmon, cod liver (and cod liver oil), sardines, brewer’s yeast and eggs.
4. Quality of Sleep. During sleep the body and brain repairs, restores, regenerates and reduces inflammation. In Autoimmune disease, sleep is essential. Aim for 8-9 hours sleep per night. Try to go to sleep by 10 or 10.30 pm as the 90 minutes before midnight is believed to be the most restorative, regenerative sleep phase. Avoid blue light from devices for 1 hour before sleep. Use meditation techniques, relaxation music, essential oils or counting sheep, whatever helps you quieten your mind to allow you to achieve good quality sleep.
5. Mindfulness-Based Stress Reduction. In recent years, mind-body practices such as mindfulness meditation, yoga and tai chi have gained recognition for their role in reducing stress and improving stress resilience. Research findings suggest that mindfulness practices may reduce inflammation in people with chronic inflammatory disease.

Research shows that the digestive condition known as leaky gut (or intestinal permeability), is a common factor in the biological mechanism that leads to the onset of autoimmune disease.

While it is easy to make the connection between the gut and digestive conditions such as food allergies, Celiac disease, Crohn’s Disease, and Ulcerative Colitis, the link to autoimmune disorders such as Type 1 Diabetes, Multiple Sclerosis or Rheumatoid Arthritis etc can be a little harder to grasp.

So, let’s break it down….

Firstly what exactly is the Gut?

The word gut is another way of referring to your gastrointestinal tract (GIT) or digestive system. Put simply, the gut is the passage through which food enters your body through your mouth, is digested (or broken down) in your stomach, beneficial nutrients are absorbed in your intestines (the small and large bowel) and then toxins and wastes are expelled via the rectum.

The innermost surface of the gut is known as the intestinal barrier.

This barrier is semipermeable as it allows certain substances to pass through it but not others.  It is the role of this barrier to protect the body by only allowing nutrients, water and electrolytes to cross into the blood stream while preventing undesirable substances from entering the body by retaining them in the gut to be excreted as waste.

How does the gut become leaky?

Disruption to the intestinal barrier in the large intestine causes damage to the tight bonds that hold the cells of the gastrointestinal lining together. When these bonds are broken, gaps form in the lining allowing contents of the gut to pass into the body via the bloodstream. This is known as increased intestinal permeability or leaky gut.

In leaky gut, pathogens, toxins, partially digested food and bacteria are able to leak through the gaps between the cells and enter the body. When these substances leak through the barrier, immune cells identify them as a potential threat and initiate an immune response in order to protect the body.

This immune response creates inflammation. In some cases, inflammation can become widespread throughout the body and contribute to many health issues, including autoimmune disease.

So, what causes disruption to the intestinal barrier?

1. Gluten. Zonulin is a protein secreted by the cells in the gut wall to stimulate the opening of gaps between cells in the intestinal barrier, to allow nutrients to pass through into the bloodstream. Gluten increases the production of Zonulin, resulting in numerous gaps in the intestinal barrier. It is believed that this mechanism is common to all autoimmune diseases and may be caused by proteins in all grains and pseudo-grains.
2. Dysbiosis. The gastrointestinal microbiome regulates the permeability of the intestinal barrier. An imbalance of good and bad bacteria living in the gut can lead to an overgrowth of pathogenic species. Pathogenic bacteria can cause inflammation in the gut lining causing damage to the intestinal barrier.
3. Sugar. Elevated blood glucose causes inflammation and alteration to intestinal cells that leads to intestinal barrier dysfunction.
4. Stress. Stress hormones can lead to inflammation which impacts the balance of gut bacteria by supporting the growth of pathogenic microbes that lead to dysbiosis and a leaky gut.
5. Alcohol. In addition to affecting the microbiome, alcohol has a direct effect on the intestinal barrier , causing cellular damage and increased permeability.

Finally, how does leaky gut lead to Autoimmune Disease?

For people with a predisposition to AID, the activation of the immune system, as a result of barrier disruptors entering the bloodstream, can lead to the production of autoantibodies – antibodies produced by the immune system that attack the body’s own tissue.

Autoantibodies are stimulated by the presence of inflammation when the body’s back-up system, which eliminates or regulates the cells that produce autoantibodies, fails and the immune system initiates an attack on the tissues.

Autoantibodies can attack local, gastrointestinal tissue leading to conditions such as Inflammatory Bowel Disease and Coeliac disease but they can also travel in the bloodstream and affect joints, organs and tissue anywhere in the body.

The good news is that leaky gut is reversible, and when your gut heals, it is possible to resolve Autoimmune Disease or achieve remission.

Using microbiome stool testing we can rebalance the bacteria in the gut. We can also use an elimination diet like AIP to reduce inflammation. By focusing on diet and lifestyle factors and microbiome modulation we can reverse leaky gut, regulate the immune system and resolve autoimmune symptoms.

Five Ways to Support Gut Healing:

1. Anti-inflammatory foods. Inflammation is one of the main drivers in AID and leaky gut. Including anti-inflammatory foods helps to heal the gut and manage AID symptoms. Anti-inflammatory foods include turmeric and Omega-3-rich oily fish (salmon, sardines, mackerel, anchovies, herring).
2. Probiotics. Eating fermented foods are an excellent way to increase beneficial bacteria in the gut to improve the microbiome balance. Non-dairy fermented foods include sauerkraut, kimchi, kombucha, coconut kefir and apple cider vinegar.
3. Prebiotics. Prebiotics are a type of dietary fibre that feed the good bacteria in your gut. Prebiotic foods include onion, garlic, leek, asparagus, artichoke and bananas. Using targeted supplements like PHGG or GOS can also be beneficial.
4. Glutamine. Glutamine is an amino acid which helps to tighten the gaps between the epithelial cells of the gut lining and improve barrier permeability. Glutamine is found in foods such as beetroot, cabbage, Brussel sprouts, grass-fed meat, seafood, bone broth, and grass-fed gelatin.
5. Reduce stress. Reducing stress is essential in order to reduce inflammation and to support gut healing and healthy immune function. Introducing techniques such as daily meditation, deep breathing or mindfulness practices helps to calm the nervous system, reduce stress and improve sleep.

To find out more about Leaky Gut or the Autoimmune Protocol and how it can work for you, book in for a Complimentary Discovery Session.

Autoimmune disease is a malfunction of the immune system.

The fundamental role of the immune system is to protect the body from invading pathogens such as viruses and bacteria. In Autoimmune Disease (AID), the immune system mistakenly recognizes the body’s own tissues as a threat and produces autoantibodies. This results in inflammation and damage to cells, tissues and organs which can impair normal functioning.

Autoimmune Conditions

Autoimmune disease affects around 5% of Australians and there are around 80 different known autoimmune conditions, with many more diseases that are suspected to be autoimmune in origin. Many are difficult to diagnose and even more difficult to treat. Most autoimmune diseases are chronic and lifelong, and their incidence is increasing year on year in most countries around the world.

Some of the more common autoimmune diseases include: Coeliac Disease, Rheumatoid Arthritis, Multiple Sclerosis, Hashimoto Thyroiditis, Type 1 Diabetes, Inflammatory Bowel Disease (including Ulcerative Colitis and Crohn’s Disease) and Psoriasis. Fibromyalgia and Chronic Fatigue Syndrome are conditions that are suspected to have autoimmune origins.

Why does the Immune System malfunction?

Though the exact causes of autoimmune disease remain unknown, there are certain risk factors that increase the chances of developing an autoimmune condition.

Genetics accounts for approximately one third of this risk, while the remaining risk is thought to come from environmental triggers such as exposure to pollution, toxins, viruses, intestinal dysbiosis (causing leaky gut) and diet and lifestyle factors.

So what does this mean for you?

This means that autoimmune disease is directly linked to your food choices and how you choose to live your life. What this suggests is that you can manage your autoimmune disease by changing your diet and making more informed choices about sleep, activity, and stress.

The Autoimmune Protocol

The Autoimmune Protocol (AIP) is a comprehensive program which focuses on diet and lifestyle factors known to be important modulators of immune function. Healing is supported by the removal of inflammatory stimuli to reduce the chronic inflammation that causes tissue damage.

That may seem like a lot to ‘digest’, so a certified AIP practitioner can help you put this into practice.

The Autoimmune Protocol provides guidelines for both diet and lifestyle changes to successfully manage the symptoms of autoimmune disease.

About the AIP Diet

The AIP diet consists of an elimination strategy, cutting out the foods that are most likely to be holding back our health. After a period of time, many of the excluded foods, especially those that have nutritional merit, can be reintroduced.

The AIP diet provides balanced and complete nutrition by prescribing nutrient dense foods while avoiding processed & refined foods.

The AIP Lifestyle

Lifestyle factors including high stress, poor sleep and minimal activity can contribute to inflammation and increase the risk of immune dysfunction leading to the onset or flare up of autoimmune disease.

The AIP provides strategies for improved sleep, stress management and regular physical activity as these are important immune modulators and are key to successfully managing AID.

Is this lifestyle difficult to maintain?

Autoimmune diseases are difficult to manage and at times can feel out of control.

By adopting diet and lifestyle strategies, such as the Autoimmune Protocol, the frequency and severity of symptoms may be reduced and quality of life improved.

If you are someone who has been recently diagnosed with an AID, or maybe you have been struggling to manage your AID for some time, the Autoimmune Protocol is for you. Book in for a Complimentary Discovery Session with Vicky to find out more. https://thenutritionfactor.com.au/book-appointment/